THE EFFECTIVENESS OF ROSE FLOWER (ROSA CHINENSIS JACQ) ON CANDIDA ALBICANS COLONIES IN JELLY (SABOURAUD DEXTROSE AGAR) MEDIA
PDF

Keywords

rose flower (Rosa Chinensis Jacq)
Candida Albicans
Sabouraud Dextrose Agar

How to Cite

Widyana, E. D., Tarsikah, T., & Naimah, N. (2019). THE EFFECTIVENESS OF ROSE FLOWER (ROSA CHINENSIS JACQ) ON CANDIDA ALBICANS COLONIES IN JELLY (SABOURAUD DEXTROSE AGAR) MEDIA. Public Health of Indonesia, 5(1), 8–13. https://doi.org/10.36685/phi.v5i1.220

Abstract

Background: Approximately 90% of women in Indonesia have the potential to experience fluor albus. Fluor albus is mostly caused by Candida Albicans. Candida Albicans is a fungus that often causes infections on people. Herbal medicine is one alternative that can be used as a raw material for anti-fungial medication of Candida Albicans.

Objective: The purpose of this study was to determine effectiveness of rose flower (Rosa Chinensis Jacq) on Candida Albicans colonies.

Methods: This research was an experimental study with posttest only control group design, using four repetitions with a concentration of 7.5%, 10%, 12.5%, 15% and 17.5%. The hypothesis test used was One-way ANOVA (Analysis of Variance) with a significance level of 0.05.

Results: The result shows that 7.5% concentration, the growth of the colonies was 148.75 CFU/ml; at 10% concentration, the growth of the colonies was 123 CFU/ml; at 12.5%, the growth of the colonies was 86 CFU/ml, at 15%, the growth of the colony was 29 CFU/ml; at 17.5 %, the colony growth was 0, so it can be concluded the higher concentration of rose extract, the lower number of Candida Albicans colonies.

Conclusion: Rose extract (Rosa Chinensis Jacq) is effective in inhibiting the growth of the Candida Albicans fungus with minimum killing levels of 17.5%. Further studies on toxicity test on rose extracts on Candida Albicans are necessary.

https://doi.org/10.36685/phi.v5i1.220
PDF

References

Adamczak, A., Buchwald, W., ZieliÅ„ski, J., & Mielcarek, S. (2012). Flavonoid and organic acid content in rose hips (Rosa L., sect. Caninae DC. EM. Christ.). Acta biologica cracoviensia series botánica, 54(1), 105-112.

Braner, L. (1993). Antimicrobial in Food. New York: Marcel Dekker. Inc.

Cai, Y.-Z., Xing, J., Sun, M., Zhan, Z.-Q., & Corke, H. (2005). Phenolic antioxidants (hydrolyzable tannins, flavonols, and anthocyanins) identified by LC-ESI-MS and MALDI-QIT-TOF MS from Rosa chinensis flowers. Journal of agricultural and food chemistry, 53(26), 9940-9948.

Chandranita, A. (2008). Gawat Darurat Obstetri Ginekologi dan Obstetri Ginekologi Sosial Untuk Profesi Bidan. Jakarta: EGC.

Deacon, J. W. (1997). Modern mycology. London: Blackwell Scientific Publication.

Orhan, D. D., í–zçelik, B., í–zgen, S., & Ergun, F. (2010). Antibacterial, antifungal, and antiviral activities of some flavonoids. Microbiological research, 165(6), 496-504.

Roman, I., Stćƒnilćƒ, A., & Stćƒnilćƒ, S. (2013). Bioactive compounds and antioxidant activity of Rosa canina L. biotypes from spontaneous flora of Transylvania. Chemistry Central Journal, 7(1), 73.

Simatupang, M. M. (2009). Candida albicans. Retrieved from http://repository.usu.ac.id/bitstream/handle/123456789/1935/09E01452.Pdf?sequence=1

Singh, S. D., Robbins, N., Zaas, A. K., Schell, W. A., Perfect, J. R., & Cowen, L. E. (2009). Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin. PLoS pathogens, 5(7), e1000532.

Tripathi, G., Wiltshire, C., Macaskill, S., Tournu, H., Budge, S., & Brown, A. J. (2002). Gcn4 co"ordinates morphogenetic and metabolic responses to amino acid starvation in Candida albicans. The EMBO Journal, 21(20), 5448-5456.

Van Melderen, L. (2001). Molecular interactions of the CcdB poison with its bacterial target, the DNA gyrase. International journal of medical microbiology, 291(6-7), 537-544.

Yatim, F. L. (2005). Penyakit kandungan: myoma, kanker rahim/leher rahim dan indung telur, kista, serta gangguan lainnya. Jakarta: Pustaka Populer Obor.

Authors who publish with Public Health of Indonesia agree to the following terms:

  1. Authors retain copyright licensed under a Creative Commons Attribution-NonCommercial CC BY-NC 4.0, which allows others to remix, tweak, and build upon the authors' work non-commercially, and although the others' new works must also acknowledge the authors and be non-commercial, they don't have to license their derivative works on the same terms.
  2. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access). Authors can archive pre-print and post-print or publisher's version/PDF.

Downloads

Download data is not yet available.